Steven L Carroll Selected Research

Neurofibrosarcoma (MPNST)

1/2021	R-Ras subfamily proteins elicit distinct physiologic effects and phosphoproteome alterations in neurofibromin-null MPNST cells.
10/2019	ErbB4 promotes malignant peripheral nerve sheath tumor pathogenesis via Ras-independent mechanisms.
9/2018	Recent Advances in the Diagnosis and Pathogenesis of Neurofibromatosis Type 1 (NF1)-associated Peripheral Nervous System Neoplasms.
1/2017	BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells.
10/2016	Tamoxifen Induces Cytotoxic Autophagy in Glioblastoma.
3/2016	The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics.
1/2016	STAT1 and NF-κB Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells.
6/2015	Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells.
1/2015	Correction: BNIP3 Regulates AT101 [(-)-Gossypol] Induced Death in Malignant Peripheral Nerve Sheath Tumor Cells.
11/2014	Combinatorial therapy with tamoxifen and trifluoperazine effectively inhibits malignant peripheral nerve sheath tumor growth by targeting complementary signaling cascades.

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Steven L Carroll Research Topics

Disease

25	Neurofibrosarcoma (MPNST) 01/2021 - 08/2003
25	Neoplasms (Cancer) 01/2021 - 08/2003
10	Carcinogenesis 01/2021 - 11/2004
9	Neurofibroma 09/2018 - 11/2004
8	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2003
5	Neurofibromatosis 1 (Neurofibromatosis Type I) 01/2021 - 03/2013
5	Nerve Sheath Neoplasms (Nerve Sheath Neoplasm) 06/2015 - 08/2003
4	Neurofibromatoses (Neurofibromatosis) 08/2016 - 02/2006
3	Plexiform Neurofibroma 04/2014 - 01/2011
2	Glioblastoma (Glioblastoma Multiforme) 01/2020 - 10/2016
2	Breast Neoplasms (Breast Cancer) 05/2018 - 07/2013
2	Hypoxia (Hypoxemia) 01/2017 - 04/2008
2	Sarcoma (Soft Tissue Sarcoma) 10/2016 - 08/2005
2	Astrocytoma (Pilocytic Astrocytoma) 08/2005 - 06/2003
2	Glioma (Gliomas) 08/2005 - 06/2003
1	Schizophrenia (Dementia Praecox) 01/2022
1	Leukemia 01/2022
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2022
1	Sepsis (Septicemia) 01/2022
1	Nervous System Neoplasms (Neoplasms, Nervous System) 01/2021
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Teratocarcinoma 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 11/2020
1	Epilepsy (Aura) 01/2019
1	Focal Cortical Dysplasia 01/2019
1	Intellectual Disability (Idiocy) 05/2017
1	Dementia (Dementias) 05/2017
1	Down Syndrome (Down's Syndrome) 05/2017
1	Schwannomatosis 08/2016
1	Neurofibromatosis 2 (Neurofibromatosis Type II) 08/2016
1	Infections 01/2016

Drug/Important Bio-Agent (IBA)

11	Neuregulin-1 (Neuregulin 1)IBA 03/2016 - 01/2003
10	Phosphotransferases (Kinase)IBA 10/2019 - 01/2003
9	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2006
8	ErbB Receptors (EGF Receptor)IBA 10/2019 - 06/2003
8	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2016 - 11/2004
5	Tyrosine (L-Tyrosine)FDA Link 10/2019 - 01/2003
4	Neurofibromin 1 (Neurofibromin)IBA 01/2021 - 05/2012
4	Tamoxifen FDA LinkGeneric 10/2016 - 01/2011
3	ras ProteinsIBA 01/2021 - 05/2012
3	Epidermal Growth Factor (EGF)IBA 10/2019 - 02/2006
3	gossypol acetic acidIBA 01/2017 - 01/2014
3	CaspasesIBA 10/2016 - 03/2012
3	Estrogen ReceptorsIBA 11/2014 - 01/2011
3	Protein Isoforms (Isoforms)IBA 08/2005 - 08/2003
2	NeuregulinsIBA 01/2022 - 02/2006
2	GTP-Binding Proteins (G-Protein)IBA 01/2021 - 01/2011
2	Protein Kinases (Protein Kinase)IBA 10/2019 - 05/2018
2	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 10/2019 - 11/2009
2	Biomarkers (Surrogate Marker)IBA 05/2017 - 08/2016
2	GossypolIBA 01/2015 - 01/2014
2	Calmodulin (Calcium-Dependent Activator Protein)IBA 11/2014 - 01/2011
2	afimoxifene (hydroxytamoxifen)IBA 07/2013 - 01/2011
2	Estrogens (Estrogen)FDA Link 07/2013 - 01/2011
2	LigandsIBA 03/2013 - 02/2006
2	Laminin (Merosin)IBA 03/2013 - 11/2009
2	EpiregulinIBA 03/2013 - 02/2006
2	Heparin (Liquaemin)FDA LinkGeneric 03/2013 - 02/2006
2	Growth Factor ReceptorsIBA 11/2008 - 01/2005
2	Caspase 3 (Caspase-3)IBA 04/2008 - 08/2003
1	Proto-Oncogene Proteins c-etsIBA 01/2022
1	Cre recombinaseIBA 01/2021
1	enhanced green fluorescent proteinIBA 01/2021
1	Biological ProductsIBA 01/2021
1	Arsenic Trioxide (Trisenox)FDA Link 11/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2020
1	brain-derived neurotrophic factor precursorIBA 01/2020
1	ProteomeIBA 01/2020
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020
1	salinomycinIBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 10/2019
1	tyrosine receptor (receptor, tyrosine)IBA 10/2019
1	Phospholipases (Phospholipase)IBA 10/2019
1	Potassium Chloride FDA LinkGeneric 01/2019
1	K Cl- CotransportersIBA 01/2019
1	oridoninIBA 05/2018
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2018
1	gamma-Aminobutyric Acid (GABA)IBA 01/2018
1	Deferoxamine (Desferal)FDA LinkGeneric 01/2017
1	Chelating AgentsIBA 01/2017
1	IronIBA 01/2017
1	obatoclaxIBA 01/2017
1	1,1',6,6',7,7'- hexahydroxy- 3,3'- dimethyl- N5- (2- phenylpropyl)- N5'- (2- phenylpropyl)- 2,2'- binaphthyl- 5,5'- dicarboxamideIBA 01/2017
1	Messenger RNA (mRNA)IBA 01/2017
1	Uvitex SWN (SWN)IBA 08/2016
1	MitogensIBA 03/2016
1	InterferonsIBA 01/2016
1	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 06/2015
1	Alanine (L-Alanine)FDA Link 02/2015
1	Threonine (L-Threonine)FDA Link 02/2015
1	Gonadal Steroid Hormones (Sex Hormones)IBA 11/2014
1	Trifluoperazine (Stelazine)FDA LinkGeneric 11/2014
1	Apolipoproteins E (ApoE)IBA 11/2014
1	A-factor (Streptomyces)IBA 09/2013
1	EpigenIBA 03/2013
1	CollagenIBA 03/2013

Therapy/Procedure

6	Therapeutics 01/2021 - 11/2008
3	Radiotherapy 03/2016 - 08/2005
2	Drug Therapy (Chemotherapy) 01/2016 - 08/2005
1	Microspheres (Microsphere) 11/2020